Best Practices for PUPSIT Assembly Design and Operation

RECORDED WEBINAR

Sterile filtration is a critical final step in drug manufacturing, ensuring that liquid-based drug substances are free from microbial contaminants. In this webinar, discover how to design and implement Pre Use Post Sterilization Integrity Test (PUPSIT) assemblies to meet regulatory expectations and reduce operational risks. 

What you'll learn:

  • Regulatory guidance and context for PUPSIT (cGMP Annex 1)
  • Background and purpose of PUPSIT in sterile filtration
  • Step-by-step overview of integrity testing for PUPSIT assemblies:
    • Commonly used integrity test devices
    • Filter wetting considerations
    • Detailed integrity test process
    • Current trends in PUPSIT implementation

Featuring practical examples, system layout tips, and expert insights to help you navigate design challenges and optimize your filtration strategy.

Watch now on demand and get answers to audience-specific questions from the live session.

toni-schonburg

Toni Schönburg - Field Applications Engineer

Toni is a biotechnology specialist with over 16 years in the life sciences industry, focusing on filtration, single-use technologies, and custom design. He’s held technical and commercial roles at companies like Saint-Gobain, Pall, and Sartorius, and currently brings his expertise to Entegris as Field Applications Engineer.