A Material Characterization Study for AAV Process Development and Tool Selection

Recorded webinar


The potential negative interaction between biologic materials and the containers used in bioprocessing and storage is a major concern. The evaluation and selection of suitable materials are essential. With the growing adoption of adeno-associated virus (AAV) viral vectors in bioprocessing operations, careful analysis of single-use bags and processing materials previously used for monoclonal antibody and recombinant protein bioprocessing is a must.
In this webcast, experts from a materials supplier and contract manufacturing organization will walk through a case study that evaluated single-use bag material interaction and adsorptive relationship with AAV viral vector during storage. A review of the experimental methods, analytical approach, and results will provide a frame of reference to help users better understand the impact and implications material selection has on yield, process, and product loss.


Joy Xiaohui Chen
Senior Applications Engineer
Joy Xiaohui Chen has more than a decade of industrial experience, with expertise in developing single-use bioprocessing solutions including bioprocessing bags, membrane filters, and bioreactors for different pharmaceutical applications. She has previously worked at GE Life Sciences (now Cytiva) and GE Global Research in the areas of physiological monitoring, disease diagnostics and prognostics, cell and gene therapy and precision medicine.
Cari Sadowski
Cari Sadowski
Principal Scientist
Fujifilm Diosynth Biotechnologies
Cari Sadowski is a principal scientist with the science and innovation group at FUJIFILM Diosynth Biotechnologies in College Station Texas. She spent 17 years at the National Cancer Institute as a viral immunologist in the cancer and inflammation group where she studied the role viruses play in cancer. Cari moved to the U.S. Department of Homeland Security where she served as a virology scientist for threat assessment. Six years ago, she joined Fujifilm as a scientist for the analytical development group and as FUJIFILM Diosynth Biotechnologies grew, she became group leader and principal scientist of the science and innovation group.