A Material Characterization Study for AAV Process Development and Tool Selection
The potential negative interaction between biologic materials and the containers used in bioprocessing and storage is a major concern. The evaluation and selection of suitable materials are essential. With the growing adoption of adeno-associated virus (AAV) viral vectors in bioprocessing operations, careful analysis of single-use bags and processing materials previously used for monoclonal antibody and recombinant protein bioprocessing is a must.
In this webcast, hosted by Pharma IQ, experts from a materials supplier and contract manufacturing organization will walk through a case study that evaluated single-use bag material interaction and adsorptive relationship with AAV viral vector during storage. A review of the experimental methods, analytical approach, and results will provide a frame of reference to help users better understand the impact and implications material selection has on yield, process, and product loss.
Field Applications Engineer
Arianna Kalkandis is a field application engineer at Entegris. She has years of hands-on experience and expertise in cell therapy, as well as single-use bioprocessing solutions including bioprocessing bags, mesh filtration systems, and bioreactors for different pharmaceutical applications. She has previously worked at Novartis supporting a commercial CAR-T cell therapy product.
Fujifilm Diosynth Biotechnologies
Cari Sadowski is a principal scientist with the science and innovation group at FUJIFILM Diosynth Biotechnologies in College Station Texas. She spent 17 years at the National Cancer Institute as a viral immunologist in the cancer and inflammation group where she studied the role viruses play in cancer. Cari moved to the U.S. Department of Homeland Security where she served as a virology scientist for threat assessment. Six years ago, she joined Fujifilm as a scientist for the analytical development group and as FUJIFILM Diosynth Biotechnologies grew, she became group leader and principal scientist of the science and innovation group.